Marcos will square off against American wild card Taylor Fritz in the first round of the US Open. It will be their first meeting.
Marcos is riding high as he enters the final Grand Slam of the year, coming off a run to the third round at the Winston-Salem Open. He returns to New York with fond memories from 2016, when he streaked to the Round of 16. He will look to replicate the success as he enters the US Open for a 12th time.
Should he defeat Fritz, Marcos would face either sixth seed Dominic Thiem or Australian teenager Alex de Minaur. Former champion Juan Martin del Potro is also in his immediate section of the draw and could be a fourth round opponent.
